Problems under the eyes, nasolabial folds, golgo lines, marionette lines, acne scars, crater skin and so on, we also approach wrinkles on the neck and hands that show signs of age!

Face-up effect, tightening the entire face, lifting the entire face, improving pores problems, fine lines, acne scars, crater skin, hollows due to aging, wrinkles, sagging, dark circles under the eyes, hollows under the eyes, sagging around the eyes, wrinkles and saggings around the corners of the eyes, nasolabial folds, marionette lines, neck wrinkles and sagging, skin rejuvenation and so on, you can expect all the effects on a cellular level.

Skin cells will be extracted and cultured from the patient’s skin and transplanted to areas where aging problems are concerned. Natural aging care is possible by increasing and activating skin cells.

You can heal everything
and become more beautiful.

At Four Seasons Cosmetic Dermatology, patients come from all over the country to receive skin regenerative medicine treatment, and we are ranked No. 1 in terms of satisfaction with our treatment results. There are various types of stem cell (fibroblast) therapy, and there is a reason why Four Seasons continues to be chosen.

The world’s first and most powerful pyramid-shaped skin regeneration treatment know-how that can only be done at our clinic has great anti-aging effects!
Total pack triple effect

【Important】

As we age, the number of fibroblasts decreases and the quality of the cells deteriorates, causing the skin to become thin and dry, forming wrinkles and sagging.
Additionally, the number of vascular endothelial cells and epithelial cells is decreasing, resulting in poor blood flow and reduced skin turnover.

When transplanting fibroblasts into such a base skin condition, b-FGF (artificial growth factor) is added to promote angiogenesis and proliferate the injected fibroblasts in order to improve cell retention.

b-FGF is originally a preparation that is sprayed onto ulcerated areas to promote the improvement of serious skin ulcers in areas with poor blood flow, such as bedsores. Subcutaneous injection is not originally recommended as there is a risk of side effects such as lumps due to its strong tissue proliferation effect.

The concentration of b-FGF added in the aforementioned fibroblast transplantation is less than half that of PRP, and the risk is even lower. However, the possibility of lumps still remains.
Therefore, our clinic proposes a new pyramid treatment that uses only your own cells and provides the maximum effect without the risk of lumps.

First, using ACRS and PRP to activate weakened fibroblasts. Once the blood flow condition has improved, the fibroblasts will be transplanted, which promotes the proliferation of the transplanted cells and improves wrinkles and sagging.

Moreover, since no artificial b-FGF is added, there is no risk of excessive proliferation and swelling, and it is possible to improve formed scars, especially pores, acne scar crater skin, and wrinkles, which can only be achieved with PRP skin regeneration therapy and ACRS therapy. Almighty skin regeneration can now be greatly expected due to the synergistic effect.

We will select the necessary pyramid treatment based on your age and symptoms. We also adjust the amount of stem cells injected according to the symptoms, and propose customized treatments for each customer.

However, b-FGF-added PRP injection is becoming popular as a treatment for injecting and inflating parts into areas where dents are concerned, such as dark circles under the eyes. Although it is highly effective in improving dents, it can also cause lumps, and there have been some cases where effective treatments to eliminate these lumps have been lacking, resulting in disastrous outcomes. Currently, research is progressing and the risk of lumps has been significantly reduced. However, adverse events have not been completely eliminated.

We believe that skin regeneration and stem cell (fibroblast) treatment is not about「stopping the hands of the clock」， but rather「turning the hands back a few years and slowing its progress」.For example, skin rejuvenation involves「turning back the clock」on the skin itself from the outside through medical treatment.

Botox injections and hyaluronic acid injections, which are injection treatments for aging symptoms such as wrinkles and sagging skin, can be effective immediately after treatment.
However, since it is a symptomatic treatment, the effects cannot be sustained unless treatment is continued regularly.

Aging will progresses, so if you don’t do anything about it, aging-related problems such as wrinkles and sagging skin still will naturally increase.
Therefore symptomatic treatment must be repeated each time.
Stem cell (fibroblast) treatment, which is a type of skin regeneration medicine, is a treatment in which the patient’s current healthy skin cells (fibroblasts) are extracted, cultured, and reinjected into areas of skin where aging is a concern.

Stem cell (fibroblast) treatment is an anti-aging method that can rejuvenate the skin starting from cells, and is called skin regeneration medicine and stem cell (fibroblast) therapy. When a person is born, there are 300 million stem cells (fibroblasts), which decrease with age. In order to rejuvenate your skin, we use advanced medical care to cultivate your own healthy stem cells (fibroblasts), multiply them tens of thousands of times, and then transplant (re-inject) them with stem cell injection. By fixing it in your own cells and achieving cell division, you can rejuvenate your skin day by day. This allows for fundamental skin treatment,「skin age rejuvenation」,and you are reborn as your younger self.

By culturing your own healthy stem cells (fibroblasts) and injecting them, you can rejuvenate your skin through fundamental skin regeneration and achieve an almighty beautiful skin effect.

The goal of anti-aging is to slow down, as much as possible, the angle of the aging curve of the body, which rapidly declines with the appearance of aging after a person stops growing.
If we can postpone the deterioration of our bodies, which is said to occur at the age of 60, until we are 80 or older, we will have slowed down the rate of aging.
Looking at it from the other side, the fact that even at the age of 80, the deterioration remains at the same level as that of a 60-year-old can also be said to indicate that the person remains 20 years younger.

An important factor essential to anti-aging is improving the quality of your daily life, such as diet, sleep, exercise, beauty, and stress.
However, it cannot be denied that there are some areas where aging cannot be compensated for with just these factors.
Therefore, a different approach to aging is needed, using advanced medical care to regenerate the skin.
As such different approaches, current advanced regenerative medicine includes「stem cell therapy」,in which only your own healthy stem cells (fibroblasts) are cultured and reinjected, 「PRP skin regeneration therapy」, in which platelets are injected, and 「ACRS Therapy」, in which adjusts the balance of inflammation in the body.These three major methods have been established as representative skin regeneration medicine.

Cells keep their lineage alive by dividing repeatedly, but in reality, the cells of multicellular organisms do not repeat dividing indefinitely. This is because individuals usually have a finite lifespan.
However, if some cells are removed and cultured, this restriction disappears.
Stem cell (fibroblast) therapy uses this method to increase the number of cells that can divide indefinitely to maintain their lineage and return them to the skin.

Taking care of the skin itself from the outside through skin care and medical treatment, rejuvenating the skin is equivalent to「turning back the clock itself」.
At our clinic, we believe that anti-aging means「turning the hands back a few years and slowing its progress」.

Download the treatment process here ▶

Based on the「Triple regeneration therapy」of stem cell (fibroblast) therapy, PRP skin regeneration therapy, and ACRS therapy, we will first regenerate the skin of your entire face (anti-aging starting from the cells), rejuvenate you with its effects, and rejuvenate your youth. Revives the natural contours of the skin.
*Treatments involving only stem cell regenerative therapy are also possible.

Only「your own healthy stem cells (fibroblasts)」made through culture are injected into your skin, and cell regeneration therapy semi-permanently improves pores, acne scars, enlarged pores, crater skin. It removes and improves dark circles under the eyes, nasolabial folds, sagging skin, tightens the skin, and wrinkles, leading to beautiful skin and a beautiful woman with the translucency of your youth as a result of fundamental treatment.

Bring out your beauty to the fullest without cutting your skin or changing your DNA through plastic surgery.

After your skin is regenerated, you will have the firm and beautiful skin of your youth. (*There is almost no downtime and no one will notice after the treatment)

Furthermore, for those who wish to have contouring done even more than mentioned above, we also offer worry-free and error-free contouring treatment through「collaboration between counselors and doctors with professional design capabilities」.As a regenerative design clinic, Four Seasons places emphasis on facial contours, especially design, and uses regenerative medical beauty and the best design that suits you to create a beautiful woman with beautiful and satisfying skin.
Four Seasons Cosmetic Dermatology is the only clinic in Hyogo Prefecture that has been approved by the Ministry of Health, Labor and Welfare as a type 2 regenerative medicine for skin cell regeneration. We can provide skin regenerative medicine treatment using skin stem cell (fibroblast) treatment that everyone is looking forward to.

Facial rejuvenation, anti-aging and fundamental skin treatment

This is a cutting-edge skin regeneration anti-aging method in which only your own healthy cells are collected, cultured and multiplied thousands of times, and water light injection with over 200shots will inject them into the face and neck. By improving the aging of skin cells, it is possible to rejuvenate the entire face and neck, and treat the root cause of wrinkles, sagging, pores, tightening, and lifting.

Regenerative medicine type 2

Autologous cultured dermal fibroblast transplantation

Regenerative medicine type 3

Regenerative medicine for skin regeneration using PRP (Platelet Rich Plasma)

Regenerative medicine type 3

Regenerative medicine for hair growth using PRP (Platelet Rich Plasma)

No matter how much you culture and multiply your own cells, nothing will happen unless you have the technology to return them to your skin and fix them.
Also, there is no need to worry about pain, such as「becoming beautiful requires pain」or「becoming younger requires patience」is not necessary.
At Four Seasons Cosmetic Dermatology, we are particular about stem cells (fibroblast transplantation), which is a regenerative medicine specialty.
For fibroblast transplantation, experienced doctors will use different needles depending on the site to effectively increase the retention rate and rejuvenate the body.
Therefore, we are able to deliver regenerative medicine that will make you feel glad that you tried it.

If you are suffering from an infectious disease, you may not only multiply the cells but also the virus itself, and may infect others. So if you have, you cannot receive our treatment.
Thank you for your understanding.

The CEO of our clinic appeared live on TV and talked about why Yumi Adachi, Anna Umemiya, and other celebrities look younger, what our clinic pursues in terms of beauty, and what Four Seasons Cosmetic Dermatology focuses on. We talked about「skin regeneration treatment (stem cell (fibroblast) therapyt/PRP skin regeneration therapy」.